WitrynaThis revealed that the difference in IMF mitochondrial fatty acid oxidation between WT and KO mice can be increased approximately 2.5-fold from 13% under basal … Witrynaand IMF mitochondria, as described previously in detail (12, 28, 49). SS and IMF mitochondria were resuspended in medium 1 (100 mM KCl, 10 mM MOPS, 0.2% …
Adaptations of skeletal muscle mitochondria to exercise …
WitrynaSkeletal muscle mitochondria can be localized below the sarcolemma (subsarcolemmal, SS) or between the myofibrils (intermyofibrillar, IMF); SS and IMF mitochondria show different biochemical and ... WitrynaInterspersed throughout the contractile myofibrillar protein network are the intermyofibrillar (IMF) mitochondria, which are more elongated and interconnected (Kirkwood et al. 1986; Ogata & Yamasaki, 1997). These mitochondria provide ATP for muscle contraction and they are tightly connected to the sarcoplasmic reticulum (SR). oor ain fireside
Protein import into subsarcolemmal and intermyofibrillar skeletal ...
Witryna9 sie 2012 · IMF mitochondria in the aged heart could be more sensitive to morphology disruption either because of i) possibly more elongated/tubular mitochondrial morphology than the globular SS mitochondria , , or ii) because of greater oxidative damage to mitochondrial proteins in the intermyofibrillar compartment , which could … Witryna9 sie 2024 · Mitochondrial shape descriptors and size measurements were obtained for subsarcolemmal (SS) and IMF mitochondria on TEM micrographs from longitudinal and transversal planes. SS mitochondria were defined as structures concentrated under the sarcolemma and sometimes close to the peripherally located myonuclei. Witryna22 lis 2013 · These workers observed that p53 KO mice exhibit reduced subsarcolemmal (SS) and intermyofibrillar (IMF) mitochondrial content as well as reduced COX activity and PGC-1α expression when compared with wild-type animals. Additionally, ablation of p53 also reduced state 3 respiration and increased ROS production in IMF … oorah the challenge