WebDCEP (dexamethasone, cyclophosphamide, etoposide, and cisplatin) has proved to be an effective salvage therapy for refractory-relapsed MM patients. Little is known, however, about its potential as mobilizing therapy. The aim of this study was to evaluate the efficacy of DCEP in mobilizing PBSC and to define its toxicity. WebMar 25, 2024 · vomiting, constipation, fever. trouble swallowing, or. unusual or unpleasant taste in the mouth. Serious side effects of Etoposide include: sudden chest pain or discomfort, wheezing, dry cough or hack; easy bruising, unusual bleeding (nose, mouth, vagina, or rectum ), purple or red pinpoint spots under the skin; vision problems;
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WebJan 21, 2024 · While current regimens are often platinum-based, we present single-center data on 70 patients with RRMM who were treated with cyclophosphamide, etoposide, and dexamethasone (CED) after a median of four lines of therapy. An overall response rate of 52% was achieved after 1–6 cycles, with 23% of patients having a very good partial … WebThe incidence of lymphomas is increased in people living with HIV (PLWH). Aggressive B-cell non-Hodgkin lymphomas (NHLs) are the most common and are considered an AIDS-defining cancer (ADC). Although Hodgkin lymphoma (HL) is not considered an ADC, its incidence is also increased in PLWH. Among all HIV-related lymphomas (HRL), the … how many tesla cybertruck preorders
Multiple Myeloma Treatment Regimens - Cancer Therapy Advisor
WebMar 30, 2024 · KPS, Karnofsky Performance Scale, IPI- International Prognostic Index; R-EPOCH, rituximab-etoposide-prednisone-vincristine-cyclophosphamide-doxorubicin, R-HyperCVAD, rituximab-hyper fractionated cyclophosphamide-vincristine-doxorubicin-dexamethasone-methotrexate-cytarabine, R-DHAC-rituximab-dexamethasone … WebEtoposide also causes DNA damage through inhibition of topoisomerase II and activation of oxidation-reduction reactions to produce derivatives that bind directly to DNA. ... rifampin, dexamethasone, carbamazepine, phenobarbital, St. John’s Wort, etc) ↓ etoposide effect: ↑ metabolism of etoposide: Caution; dose of etoposide may require ... WebJun 6, 2024 · The HLH-94 protocol drastically improved the nearly uniformly fatal outcome in pediatric HLH to a long-term survival >50%. 3 The HLH-94 protocol consists of corticosteroids, typically dexamethasone, cyclosporine A (CSA), intrathecal therapy, and etoposide, to delete activated T cells and suppress inflammatory cytokine production . 6 … how many tesla cybertruck preorders 2022