Destiny trial hemicraniectomy
WebMar 21, 2014 · DESTINY II was a multicenter randomized controlled trial (RCT) of decompressive hemicraniectomy surgery vs. medical care for patients age >60 with large hemispheric ischemic strokes with brain …
Destiny trial hemicraniectomy
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WebAug 9, 2024 · In this single-center cohort of elderly patients with space-occupying MCA infarction and decompressive hemicraniectomy, the probability for survival without severe disability was low. ... A pooled analysis of individual patient data from the single-center cohort and a DESTINY 2 trial subgroup was performed to identify factors associated with ... WebMar 24, 2024 · In a more recent prospective randomized clinical trial, Decompressive Surgery for Treatment of Malignant Infarction of Middle Cerebral Artery-II (DESTINY II trial) published in 2014, the efficacy of a decompressive hemicraniectomy within 48 h after stroke onset was investigated for elderly patients aged >60 years . In this trial, while …
WebDec 19, 2024 · The initial three randomised controlled trials (DECIMAL , HAMLET and DESTINY ) considered individually or with pooled patient data analysis demonstrated that hemicraniectomy was superior to medical management alone in both survival and functional outcome measured using the modified Rankin score (mRS) where good … WebBackground and Purpose— Decompressive surgery (hemicraniectomy) for life-threatening massive cerebral infarction represents a controversial issue in neurocritical care …
WebJan 14, 2016 · All three controlled trials had an age limit of 60 years for inclusion. More recently the DESTINY II trial investigated how hemicraniectomy affects patients older than 60 years of age. ... A recent trial, DESTINY II, focusing on this elderly population of stroke-afflicted patients, found better outcomes: mRS of 0–4 present in 38% in the ... WebHofmeijer and colleagues presented the results of the HAMLET study (Hemicraniectomy After Middle cerebral artery infarction with Life-threatening Edema Trial), one of three …
WebFeb 9, 2007 · 93 patients were included in the pooled analysis. More patients in the decompressive-surgery group than in the control group had an mRS≤4 (75% vs 24%; pooled absolute risk reduction 51% [95% CI 34–69]), an mRS≤3 (43% vs 21%; 23% [5–41]), and survived (78% vs 29%; 50% [33–67]), indicating numbers needed to treat of two for …
Webfor the DESTINY Study Group* Background and Purpose—Decompressive surgery (hemicraniectomy) for life-threatening massive cerebral infarction represents a … including inland drayageWebHemicraniectomy can also be referred to as a frontotemporoparietal craniectomy. The patient is positioned supine with optional placement of a sandbag under the ipsilateral shoulder. The head is placed in a rigid 3 … including insurance premium taxWebOct 2, 2012 · Randomized controlled trials (RCT) on the treatment of severe space-occupying infarction of the middle cerebral artery (malignant MCA infarction) showed that early decompressive hemicraniectomy (DHC) is life saving and improves outcome without promoting most severe disablity in patients aged 18–60 years. It is, however, unknown … including inter aliaWebFeb 1, 2011 · Randomised trials demonstrated that early hemicraniectomy reduces mortality from about 70% to 20% without increasing the risk of being very severely … including internet directory servicesWebSince the last guideline was published, the DESTINY-II randomised trial has reported the effect of hemicraniectomy in patients over the age of 60 years. This review therefore … including interests on resumeWebEvidence base is limited by small trials and potential for systematic bias (e.g. due to lack of allocation concealment) Should only be considered if age <60 years and <48h since … including invitingWebApr 18, 2012 · Decompressive hemicraniectomy (DHC) has proven efficacious for the treatment of malignant middle cerebral artery infarction (mMCAI) only in patients less than 60 years. This study aimed to assess the effectiveness of DHC in patients up to 80. ... DECIMAL and DESTINY trials) [6, 7]. Thus, a dichotomized functional outcome analysis … including interest