Crossover junction endonuclease mus81

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August undefined, 2024

WebContributes to crossover junction endodeoxyribonuclease activity. Involved in DNA metabolic process and regulation of reciprocal meiotic recombination. Part of Holliday junction resolvase complex. ... Study presents evidence that yeast Mus81-Mms4 endonuclease contributes to cell viability in the absence of functional telomerase. This ... WebMar 1, 2024 · Mus81 is a highly conserved endonuclease with homology to the XPF subunit of the XPF-ERCC1 complex. In yeast Mus81 associates with a second subunit, …

FlyBase Gene Report: Dmel\mus81

WebMar 29, 2024 · EME2 forms a heterodimer with MUS81 (MIM 606591) that functions as an XPF (MIM 278760)-type flap/fork endonuclease in DNA repair (Ciccia et al., 2007 [PubMed 17289582]).[supplied by OMIM, Mar 2008] ... probable crossover junction endonuclease EME2, SLX2 structure-specific endonuclease subunit homolog B, essential meiotic … WebPrimePCR™ Template for SYBR® Green Assay: Mus81, Rat Reaction: 4 billion copies/200 µl desalted Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding primer assay. List Price: $164.00 Your Price: Log In Quantity: Add to Cart ... dna and plasmids

Anti-Mus81 antibody, Mouse monoclonal - Sigma-Aldrich

WebInteracts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical … WebMUS81 encodes a crossover junction endonuclease involved in cell division [43]. MUS81 endonuclease also plays a role in repairing damaged DNA, such as the repair of stalled or blocked... WebPTHR13451 CLASS II CROSSOVER JUNCTION ENDONUCLEASE MUS81 2 hits; Pfam. View protein in Pfam; PF02732 ERCC4 1 hit; SMART. View protein in SMART; SM00891 ERCC4 1 hit; SUPFAM. SSF47802 DNA polymerase beta, N-terminal domain-like 1 hit; SSF52980 Restriction endonuclease-like 1 hit; MobiDB. dna and rna group

A meiotic XPF–ERCC1-like complex recognizes joint molecule ...

MUS81 SGD

WebThis constitutes an important mechanism of crossover avoidance, which otherwise can lead to loss of heterozygosity and cancer predisposition. ... The structure-specific endonuclease MUS81 contributes to replication restart by generating double-strand DNA breaks. ... Coordinated actions of SLX1–SLX4 and MUS81–EME1 for Holliday junction ... WebFeb 21, 2006 · Function Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed … dna and rna quizlet biologyWebCrossover junction endonuclease MUS81 (Candida albicans SC5314) Protein Target - PubChem Apologies, we are having some trouble retrieving data from our servers... dna and rna upsc

"WebMus81 is homologous to the XPF subunit of the ERCC1–XPF nucleotide excision repair endonuclease. 448,449 Eme1 is a noncatalytic subunit. 420,448,449 Mus81–Eme1 … " - Crossover junction endonuclease mus81

Crossover junction endonuclease mus81

WebMay 28, 2014 · Crossover junction endonuclease MUS81Chains: A, C, E, G Molecule details › Chains:A, C, E, G Length:306 amino acids Theoretical weight:34.02 KDa Source organism:Homo sapiens Expression system:Escherichia coli UniProt: Canonical: Q96NY9(Residues: 246-551; Coverage: 56%) Gene name:MUS81 Sequence … WebMar 1, 2024 · crossover junction endonuclease MUS81 [EC:3.1.22.-] Organism: dre Danio rerio (zebrafish) Pathway: dre03440 : Homologous recombination: dre03460 : Fanconi anemia pathway ... 406839 (mus81) 03460 Fanconi anemia pathway 406839 (mus81) 09180 Brite Hierarchies 09182 Protein families: genetic information processing 03400 …

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Webcrossover junction endonuclease MUS81; EC 3.1.22; EC 3.1.22.-FLJ21012; FLJ44872; MUS81 endonuclease homolog (S. cerevisiae) MUS81 endonuclease homolog (yeast) SLX3 structure-specific endonuclease subunit homolog; SLX3; Background. Mus81 and EME1 constitute a heterodimeric endonuclease that has been implicated in mitotic and … WebCrossover junction endonuclease Mus81: Homologous_superfamily: IPR011335: Restriction endonuclease type II-like: Homologous_superfamily: IPR027421: DNA …

WebAbx , Every proteiIdentifier , Protein names , Gene names , Cross reference refseq , Length WebCrossover junction endonuclease EME1 is an enzyme that in humans is encoded by the EME1 gene. [5] [6] It forms a complex with MUS81 which resolves Holliday junctions. In mammalian cells the EME1/ MUS81 protein complex is redundant for DNA damage repair with GEN1 endonuclease. [7]

WebCrossover junction endonuclease Mus81 protein was identified by screening a human cerebellum cDNA library with a probe from the yeast Mus81. The human Mus81 has 551 amino acids with a molecular mass of 59 kDa. The highest sequence similarity between different species is around the VERKX3D motif. WebJan 5, 2024 · This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures.

WebNov 19, 2024 · Data indicate that SLX1 and MUS81-EME1 nucleases act together to resolve Holliday junctions (HJs) in a manner that requires tethering to SLX4. FBH1 helicase activity is required to eliminate cells with excessive replication stress through the generation of MUS81-induced DNA double-strand breaks.

WebNov 19, 2024 · Data indicate that SLX1 and MUS81-EME1 nucleases act together to resolve Holliday junctions (HJs) in a manner that requires tethering to SLX4. FBH1 helicase … dna and rna graphic organizerWebMus81 is homologous to the XPF subunit of the ERCC1–XPF nucleotide excision repair endonuclease. 448,449 Eme1 is a noncatalytic subunit. 420,448,449 Mus81–Eme1 … dna and rna 24WebMouse Gene Mus81 (ENSMUST00000124334.7) from GENCODE VM23 Comprehensive Transcript Set (only Basic displayed by default) Description: Mus musculus MUS81 structure-specific endonuclease subunit (Mus81), transcript variant 1, mRNA. (from RefSeq NM_027877) ... DESCRIPTION: RecName: Full=Crossover junction endonuclease … dna and rna overviewWebProduct Specs; Item Recombinant Neurospora crassa Crossover junction endonuclease mus-81 (mus-81), partial; Company MyBioSource.com; Price Supplier Page View Company Product Page; Catalog Number MBS1286867; Purity >90%; Type Recombinant Protein; Molecule Name Crossover junction endonuclease mus-81 (mus-81), partial; Format … dna and rna sugarWebFeb 22, 2014 · The Mus81-Eme1 complex is a structure-selective endonuclease with a critical role in the resolution of recombination intermediates during DNA repair after interstrand cross-links, replication fork collapse, or double-strand breaks. dna and rna imagesWebSubunit of structure-specific Mms4p-Mus81p endonuclease; cleaves branched DNA; involved in DNA repair, replication fork stability, and joint molecule formation/resolution … dna ao3WebThis gene encodes a structure-specific endonuclease which belongs to the XPF/MUS81 endonuclease family and plays a critical role in the resolution of recombination … dna animal