WebCLEC7A is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with a partial immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition …
Signaling C-type lectin receptors in antimycobacterial immunity
WebMar 2, 2024 · CTLs作为一种重要的模式识别受体(pattern recognition receptor, PRR),在识别微生物PAMPs、抵御微生物感染中发挥着重要作用 。 本文主要综述近年来CTLs在感染免疫中作用的研究进展。 智库是健康界打造的医健领域在线互动式文档共享平台,拥有医院管理、医健产业 … 赢在精细——公立医院高质量发展之管理创新研修班. 众所周知,今年6月,国务院 … 巴黎大学公立医院集团是欧洲最大的医疗机构,共有39家医院分布在巴黎大区范围 … WebFc epsilon RI (FcεRI) is a high-affinity receptor for the Fc region of IgE. On the mast cells and basophils, Fc epsilon RI is a tetramer with one α-chain, one β-chain, and two γ-chains connected by two disulfide bridges. And it exists as a trimeric complex consisting of one β-chain and two disulfide-bonded γ-chains on dendritic cells ... sonshine preschool parma
RIG-I-like Receptor (RLR) Signaling Pathways: R&D …
WebOverview of RIG-I-like Receptors. The RIG-I-like receptors (RLRs) are a family of cytosolic pattern recognition receptors that are essential for detecting viral RNA and initiating the innate immune response. The RLR … WebC-type lectins in immunity and homeostasis. The C-type lectins are a superfamily of proteins that recognize a broad repertoire of ligands and that regulate a diverse range of … WebDuring the last two decades, C-type lectin receptors (CLRs) have been demonstrated to play key roles in initiating the host immune response against fungal infection. It is well established that CLRs, such as Dectin-1, Dectin-2, Dectin-3 and Mincle recognize the cell wall component from the infected microorganisms by using their carbohydrate ... son shine outreach center